Free One Day Workshop- Mediation Analysis: Challenges and Novel Approaches – Bristol 11th March

Red arrows

Free one day workshop sponsored by the Society for Social Medicine and INTERSTELA*

Friday 11th March 2016 @ Engineers’ House, The Promenade, Bristol, BS8 3NB

Mediation analysis is widely used to understand the pathways and mechanisms linking exposures and outcomes. Traditional methods for mediation analysis have several limitations including: i) susceptibility to confounding and bias when the mediator is measured with error, ii) interactions between the exposure and mediator are not accounted for, iii) collider bias may be induced by conditioning on the mediator in the presence of mediator-outcome confounders, iv) the models cannot be estimated if a descendent (consequence) of the exposure confounds the mediator-outcome association (‘intermediate confounding’).  This workshop will outline the challenges of traditional methods for mediation analysis and some of the novel approaches based on counterfactual theory or instrumental variable methods (including Mendelian Randomization).

Speakers and topics:

11.00  Coffee and welcome Laura Howe, MRC Integrative Epidemiology Unit at the University of Bristol
11.30  Mediation analysis and pitfalls of traditional methods Richard Emsley, University of Manchester
12.15  Novel mediation methods

based on counterfactual theory

Rhian Daniel, London School of

Hygiene and Tropical Medicine

13.00  Lunch
14.00  Poster session and facilitated discussion groups
15.00  Instrumental variable methods for mediation analysis, with applied examples from epigenetic epidemiology Rebecca Richmond, MRC Integrative Epidemiology Unit at the University of Bristol
15.45  Summary Kate Tilling, MRC Integrative Epidemiology Unit at the University of Bristol
16.00  Close of day

Posters:

There will be a dedicated poster session for participants to present their work on any aspect of mediation analysis. Please send a short (200 word) abstract to Liz Green (liz.green@bristol.ac.uk) by Friday 19th February if you wish to present a poster

Travel bursaries:

  • Up to 5 travel bursaries (maximum £200 per person) are available for early career researchers who are members of the Society for Social Medicine. Please contact Liz Green (green@bristol.ac.uk) to apply for a bursary
  • Up to 5 travel bursaries (maximum £200 per person) are available for participants who are presenting posters on epigenetic research. Please contact Liz Green (green@bristol.ac.uk) to apply for a bursary

Registration:

Registration is free, but pre-booking is essential and spaces are limited. Please contact Liz Green (liz.green@bristol.ac.uk) asap, and no later than Friday 19th February, to reserve your space.

*INTERpreting epigenetic signatures in STudies of Early Life Adversity (INTERSTELA):

A research network co-funded by the ESRC and BBSRC

ESRC

SSM

BBSRC

Uni of Bristol

 

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